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How long does nitrofurantoin stay in your system?

How long does nitrofurantoin stay in your system?

The primary purpose of nitrofurantoin is to kill the bacteria that result in UTIs. After taking it for several days, you will notice a decrease in its symptoms. It indicates that your body is returning to balance with the healthy amount of bacteria in the urinary tract.

Nitrofurantoin is a powerful antibiotic drug prescribed by most physicians. How long does nitrofurantoin stay in your system? It’s difficult to say the exact date of how long it can stay, as every individual varies from the other.

Let’s dig into the details to find out, “How long does nitrofurantoin stay in the system?”

How long does nitrofurantoin stay in your system?

We can not tell the exact amount of time, but according to the research, it stays for around 24 hours in the body. But still, there are a lot more things involved in it. Because in medicine, the active compound nitrofurantoin is eliminated way faster, around 4 to 5 hours after having the dose.

What is Nitrofurantoin?

Nitrofurantoin is a drug that many doctors recommend. It is a urinary antiseptic drug used to treat infections related to the lower urinary tract. It is a commonly available generic medication.

Usage of Nitrofurantoin

Nitrofurantoin is prescribed for treating UTIs that fall into two major categories.

Lower tract UTIs:

The lower tract UTIs, also known as bladder infections, are the typical type of urinary tract infection used to treat the urinary tract. It means it’s for the areas from the urethra to the bladder.

Upper tract UTIs:

Upper tract UTIs are the more severe types of kidney infections. Upper UTIs are generally the result of untreated lower UTIs that can spread toward the kidneys. Its most common symptoms include fever, nausea, lower back or side pain, and body chills.

Antibiotics can help treat kidney diseases, but in severe cases, you may need to go to the hospital to prevent organ damage or renal failure.

Generally, nitrofurantoin is prescribed for the treatment of complicated lower tract infections. A UTI is also considered uncomplicated if someone has no urinary tract issues or other underlying conditions.

If you are already prone to urinary tract infections, your physician can prescribe small nitrofurantoin for an extended period.

Side effects of Nitrofurantoin

Nitrofurantoin is a well-tolerated drug. But some patients have occasionally observed its side effects. The most common side effect of the drug is drowsiness. Some other effects include:

These symptoms are rare among users. If you have experienced these symptoms, they will go away once you stop taking them. However, if the symptoms are persistent or get severe with time, consult your physician immediately.

Here are a few common symptoms of severe cases:

Every person has a different reaction to the drug. If you think your symptoms are severe to the drug, consult your doctor immediately.

How long does Nitrofurantoin take to show benefits?

Nitrofurantoin is available in different formulations. Macrobid is among the commonly available ones. But there are many types of formulation. In Addition, the Macrobid capsule has two different types of nitrofurantoin to make its effect last longer.

To better understand how long nitrofurantoin takes to show benefits, let me explain it by answering, “How long does nitrofurantoin stay in your system?” To illustrate the speed of this procedure, scientists use the term known as the half-life.

Half-life is the time that half of the drug takes to be inactivated. Generally, it takes around 5-6 half-lives to eliminate a drug from the system.


Will Nitrofurantoin benefit in 3 days of intake?

If you use nitrofurantoin to treat urinary tract infections, use it for at least 3 to 7 days. To stop the urinary tract infections from returning, your doctor may prescribe a small dosage for an extended period.

Is nitrofurantoin a strong antibiotic?

Yes, nitrofurantoin is a potent and effective antibiotic. It benefits many urinary tract bacteria like staphylococcus, klebsiella, enterobacter, enterococcus faecalis, and E. coli.

Does nitrofurantoin clean your system?

Nitrofurantoin is a nitrofuran antibiotic. This medicine is collected in the urine and kills the bacteria in your urinary tract. It kills the bacteria by damaging an essential blocking protein that bacteria need for survival.

Can Nitrofurantoin treat all sorts of infections?

When you take nitrofurantoin, your body quickly filters the medicine from the blood and collects it in your pee. It only benefits when you have a urinary tract infection as it is already concentrated in the infection site. But it doesn’t mean nitrofurantoin will not work for any other infection.


Now you have a detailed answer to how long nitrofurantoin stays in your system. Generally, it takes around 24 hours to get out of the system. However, if you experience any of its symptoms, stop using the drug and consult your doctor immediately to avoid any complications or prolonged side effects.

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