Berberine, how long does it take to work?

After ingestion, berberine enters the small intestine, where it enters the bloodstream. The blood takes it to the different cells of the body. It activates and deactivates the reaction of specific proteins and enzymes in the body.

Berberine has anti- cancers effects, targeting the cancer path inside the cell. Targeting the specific proteins interferes with the invasion of cancerous cells and stops their metastasis by targeting the protein. Berberine works on the root cause of the issue, so it takes at least 6 months to work on the leading cause.

Berberine benefits are not limited to diabetes or cancerous cells. But it also aids in the breakdown of lipids, storage of fat, and glucose formation. Because berberine has anti-inflammatory properties and controls the blood sugar level, that potentially benefits in losing weight and belly fat.

Berberine, how long does it take to work

You can’t feel the effects of the berberine if you only take it for a few days. Taking it for more than three months is vital to see its potential benefits. According to the studies, you can see the help of the supplement after taking the berberine for at least three months.

A study on the benefit of berberine for obesity states that 500mg of berberine supplement 3 times a day results in a noticeable weight reduction. All the participants, on average, lost around 5 pounds in total. There was a reduction in fat by 3.6% with the help of berberine.

The participants’ cholesterol levels were reduced by 12.2%, which is significant. There was a 23% reduction in the triglyceride level. Even with the substantial weight loss, a decrease in cholesterol and lipids reduced the risk of stroke, hypertension, and cardiovascular disease.

Another study examines the effectiveness of having 300 mg of berberine supplement for twelve’s weeks three times a day to reduce the participant’s body mass index. The study results reveal that berberine reduces the BMI of the treatment group from 31.5 to 27.4. A BMI of 30 or more is in the obese category, while a BMI of 25 to 29 is included in the overweight.

The research reveals that the berberine supplement can potentially move the person from the obese category to the overweight. It’s also vital to look out for other lifestyle factors when you are taking berberine supplements.

Based on the studies, berberine intake for 12 weeks and three months is necessary to see positive results in BMI, sugar control, weight, cholesterol, and triglycerides. However, it’s essential to be cautious when interpreting the findings, as in both studies, the sample size was minimal.

Uses and Effectiveness

The berberine supplement has many benefits like controlling the blood glucose level and many as mentioned below:

Diabetes: Berberine supplement benefits people with diabetes by having control of their blood sugar levels. The early studies suggest that taking a berberine supplement for three to five months per day helps regulate the blood glucose level.
PCOS: PCOS is an ovary disease generally known as polycystic ovary syndrome. According to the studies, PCOS in females can decrease triglyceride and enhance cholesterol and blood glucose levels. Berberine also benefits in reducing the waist-to-hip ratio and testosterone levels in women. Like metformin, berberine can reduce the concentration of blood sugar and enhance cholesterol concentration. Besides, in PCOS women, it increases the pregnancy rate.
Cholesterol level: Berberine benefits users in controlling their high cholesterol levels. Taking 500mg thrice a week for a year can reduce the low-density lipoproteins, poor cholesterol, and triglyceride concentration.
Canker sores: Research demonstrates that applying a gel with berberine content reduces the canker sores, oozing, ulcer volume, and redness.
High blood pressure: Taking a small amount of berberine with amlodipine, a blood pressure-reducing drug, can lower systolic and diastolic pressure. It works faster than the individuals who only took amlodipine to control their blood pressure.

How should I take berberine?

Berberine, how long does it take to work? How to take berberine? How much should I take? Can I take berberine on an empty stomach? These are the few frequently asked questions. It’s always best to talk with the doctor before taking any medicine, but here are some general suggestions.

Take 500mg of berberine thrice a day. It’s the average amount in most clinical trials for blood sugar, weight, lipids, and liver diseases. Thrice a day dose is perfect for prediabetic people as well.

Try taking berberine at least 30 minutes before having your meal. It’s best to tolerate it when you take it with food. Besides, eating it at mealtime can blunt the sudden spike in blood sugar after eating food. If you don’t have any gastrointestinal issues, you can take it on an empty stomach.

Note: Always consult your doctor before adding any supplement to your dietary routine.

How long can I take berberine?

There are significantly fewer studies on berberine to determine its efficiency when taking it for more than three months. Experts are also not sure what the results will be on the person’s blood sugar, BMI, and other obesity biomarkers if it takes more than three months.

Besides, as mentioned above, berberine benefits are not limited to weight loss, and it helps treat cancer cells in animal samples. But unfortunately, there are few studies that work on examining berberine to treat different types of cancers. But the current studies conducted on animal models of berberine aid in the treatment of colon cancer. The researchers see the effectiveness of berberine after two weeks of treatment.

However, there is no clear evidence to prove berberine’s effectiveness in treating colon cancer in humans. It’s still unknown how long a person will respond to the berberine and how long we can take it without any side effects. But the study’s results are promising and open the door for future studies.

Conclusion

Most studies demonstrate berberine’s ability to lower the blood glucose level as effectively as metformin and other diabetes drugs. The expert recommends using it for at least three months.

Some people experience the benefits from the first month, while others only get marginal results. Like all the other therapies, people experience effects at different times, which may not work for everyone.

To get accurate information about the working of berberine, we recommend having an A1C result before taking berberine and after three months of its use to know its benefits. Use it in addition to a low-carbohydrate exercise and diet to get even better results.

FAQ’s

Berberine, how long does it take to work?

A study was conducted to examine berberine’s effects on people taking 500mg twice a day. It was observed that after three months of its usage, people see a significant drop in hemoglobin levels, LDL cholesterol, total cholesterol level, systolic blood pressure, and triglycerides.

How long do the berberine effects last?

Berberine has several-hour half-lives, so it only lasts for a while. Most berberine supplements have 500mg capsules, and labels recommend taking berberine thrice a day.

How long should you take berberine?

If berberine is taken by mouth, it’s possibly safe for most adults. If the recommended amount is strictly followed, you can safely take it for 6 months.

How does berberine benefit?

Berberine and berberine hydrochloride is present in many different plants like the goldenseal, turmeric tree, barberry, and Oregon grape. According to the studies, berberine help in the treatment of obesity, diabetes, inflammation, and other conditions like cancer. However, it may have some side effects like nausea or upset stomach.

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